How to Win the War on Cancer
by Michael Greger M.D. FACLM
How effective is chemotherapy for colon, lung, breast, and prostate cancer? Watch video.
Worldwide Cancer Research. Gluten contributes to the development of a very rare blood cancer
With funding from Worldwide Cancer Research, scientists in The Netherlands have revealed how gluten plays a role in the development of a rare form of cancer, for a small group of people with celiac disease.
The scientists at Leiden University Medical Center (LUMC) have shown that immune system cells, which react to gluten, produce chemicals called cytokines that can contribute to the development of a rare form of lymphoma (cancer of the white blood cells). The findings were published recently in the Proceedings of the National Academy of Sciences (PNAS). LUMC researcher and Worldwide Cancer Research scientist, Dr Jeroen van Bergen, explained “the immune system is seen as an ally in the battle against cancer, but that isn’t always the case.” Read more . . .
Worldwide Cancer Research. Potential new drugs to help both cancer and diabetes patients.
With Worldwide Cancer Research funding, scientists have created new molecules that they hope can become drugs for both cancer and diabetes. Their findings are published this week in the Journal of Medicinal Chemistry.
The chemical compounds reduce the growth and proliferation of colon (bowel) cancer cells, and increase glucose uptake into fat cells meaning they could also help diabetes patients manage their disease.
The research team from Cancer Research at Bath (CR@B), working with colleagues at the University of Oulu in Finland, designed and made two molecules to specifically stick to and switch off enzymes called tankyrases, which are involved in an important cellular process called Wnt/β-catenin signalling. Read more . . .
Worldwide Cancer Research. How tumors trick the immune system into helping them, rather than harming them.
Scientists funded by Worldwide Cancer Research at Trinity College Dublin have discovered how certain cancers hijack the immune system for their benefit, tricking it into helping rather than harming them.
The team from the Smurfit Institute of Genetics at TCD, led by professor of medical genetics, Seamus Martin, identified a molecule that sends a ‘wound-healing’ message from tumors.
“If we can disrupt this messaging system, we may be able to fight certain cancers,” said Prof Martin. The wound-healing aspect of the immune response stimulates the growth of new cells within damaged tissue and brings extra nutrients and oxygen into the injured tissue. However, cancers frequently exploit the wound-healing side of the immune system for their own ends. They can masquerade as damaged tissue to receive help from the immune system. Read more . . .
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